قياس تركيز هرمون اللبتين لدى مرضى احمرار الدم/Measurement Of Serum Leptin Concentrations Among Polycythemic Patients
Keywords:polycythemia, leptin, BMI, AGE, PCV
Leptin is important adipose tissue derived cytokines. not only regulates metabolism, but also participates in hematopoiesis. Aberrant leptin levels in patients with hematologic malignancies were observed and associates with clinical characters, such as body mass index (BMI), This study was aimed to determine the role of leptin level among polycythemic(PV) patients also study other factors such as age, body mass index ,smoking and measure heamoglobin (Hb)and packed corpuscle volume(PCV) the study involved 65 samples of polycythemic patients from Mergan hospital in Babylon city ,which subdivided into three group according to body mass index(BMI) and further subdivided to seven age group to study incidence of PV among age groups . Statistical analysis showed variable significant differences (p≤0.05) in the leptin values between all age groups of patients.while body mass index was ≤ 25 ,and there was significant differences between age groups,which increased for 20-25 and 25-30 then 35-40 years old where as low incidence for other age group ,also increased incidences in smoking patients than non smoking ( p≤0.05) Conclusion low level for leptin among polycythemic patients which may be need further studies for both sex ,and icreased incidence of PV among 20-25 and 25-30 years old .